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Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development

Differential mRNA polyadenylation plays an important role in shaping the neuronal transcriptome. In C. elegans, several ankyrin isoforms are produced from the unc-44 locus through alternative polyadenylation. Here, we identify a key role for an intronic polyadenylation site (PAS) in temporal- and ti...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Chen, Fei, Chisholm, Andrew D., Jin, Yishi
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312038/
https://ncbi.nlm.nih.gov/pubmed/28087624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.146001
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