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Considerations and complications of mapping small RNA high-throughput data to transposable elements

BACKGROUND: High-throughput sequencing (HTS) has revolutionized the way in which epigenetic research is conducted. When coupled with fully-sequenced genomes, millions of small RNA (sRNA) reads are mapped to regions of interest and the results scrutinized for clues about epigenetic mechanisms. Howeve...

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Veröffentlicht in:Mob DNA
Hauptverfasser: Bousios, Alexandros, Gaut, Brandon S., Darzentas, Nikos
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311732/
https://ncbi.nlm.nih.gov/pubmed/28228849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-017-0086-z
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