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In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts

We hypothesized that the neonatal rat heart would bring transplanted human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to maturity as it grows to adult size. In neonatal rat heart, engrafted hiPSC derivatives developed partially matured myofibrils after 3 months, with increasing...

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Publicado en:Stem Cell Reports
Main Authors: Kadota, Shin, Pabon, Lil, Reinecke, Hans, Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311430/
https://ncbi.nlm.nih.gov/pubmed/28065644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.10.009
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