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Direct control of regulatory T cells by keratinocytes

Environmental challenges to epithelial cells trigger gene expression changes that elicit context-appropriate immune responses. Here we show that the chromatin remodeler Mi-2β controls epidermal homeostasis by regulating genes involved in keratinocyte and immune-cell activation to maintain an inactiv...

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Foilsithe in:Nat Immunol
Main Authors: Kashiwagi, Mariko, Hosoi, Junichi, Lai, Jen-Feng, Brissette, Janice, Ziegler, Steven F., Morgan, Bruce A., Georgopoulos, Katia
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310986/
https://ncbi.nlm.nih.gov/pubmed/28092372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3661
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