25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression

Age-associated decline in muscle function represents a significant public health burden. Vitamin D-deficiency is also prevalent in aging subjects, and has been linked to loss of muscle mass and strength (sarcopenia), but the precise role of specific vitamin D metabolites in determining muscle phenot...

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Опубликовано в: :PLoS One
Главные авторы: Hassan-Smith, Zaki K., Jenkinson, Carl, Smith, David J., Hernandez, Ivan, Morgan, Stuart A., Crabtree, Nicola J., Gittoes, Neil J., Keevil, Brian G., Stewart, Paul M., Hewison, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310904/
https://ncbi.nlm.nih.gov/pubmed/28199350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170665
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