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Basic studies on epigenetic carcinogenesis of low-dose exposure to 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) in vitro

1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) has been widely studied as a neurotoxic substance, however, only few reports have explored its effect on carcinogenicity. Since the aberrant modification of DNA methylation occurs very early in almost all human cancers, the focus of this study...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Renjie, Cui, Yi, Xu, Yi, Irudayaraj, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310788/
https://ncbi.nlm.nih.gov/pubmed/28199384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172243
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