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Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival

During metastatic progression, circulating cancer cells become lodged within the microvasculature of end-organs, where a majority die from mechanical deformation. Though this phenomenon was first described over a half-century ago, the mechanisms enabling certain cells to survive this metastasis-supp...

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Publicat a:Nat Cell Biol
Autors principals: Furlow, Paul W., Zhang, Steven, Soong, T. David, Halberg, Nils, Goodarzi, Hani, Mangrum, Creed, Wu, Y. Gloria, Elemento, Olivier, Tavazoie, Sohail F.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310712/
https://ncbi.nlm.nih.gov/pubmed/26098574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3194
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