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Spotlight on crizotinib in the first-line treatment of ALK-positive advanced non-small-cell lung cancer: patients selection and perspectives

Around 4% of advanced non-small-cell lung cancers (NSCLCs) have an ALK rearrangement at the time of diagnosis. This molecular feature is more frequent in young patients, with no/light smoking habit and with adenocarcinoma pathological subtype. Crizotinib is a tyrosine kinase inhibitor, targeting ALK...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Lung Cancer (Auckl)
Päätekijät: Leprieur, Etienne Giroux, Fallet, Vincent, Cadranel, Jacques, Wislez, Marie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310701/
https://ncbi.nlm.nih.gov/pubmed/28210164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S99303
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