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Intraperitoneal chemotherapy of ovarian cancer by hydrogel depot of paclitaxel nanocrystals

Intraperitoneal (IP) chemotherapy is a promising post-surgical therapy of ovarian cancer, but the full potential is yet to be realized. To facilitate IP chemotherapy of ovarian cancer, we developed an in-situ crosslinkable hydrogel depot containing paclitaxel (PTX) nanocrystals (PNC). PNC suppressed...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Sun, Bo, Taha, Maie S., Ramsey, Benjamin, Torregrosa-Allen, Sandra, Elzey, Bennett D., Yeo, Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310690/
https://ncbi.nlm.nih.gov/pubmed/27238443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.05.056
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