Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Are Immunogenic, Alter Cytokine Profile and Aid in Intracellular Survival

Mycobacterium tuberculosis (M. tb) has two peptidyl-prolyl isomerases (Ppiases) PpiA and PpiB, popularly known as cyclophilin A and cyclophilin B. The role of cyclophilins in processes such as signaling, cell surface recognition, chaperoning, and heat shock response has been well-documented. We pres...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Pandey, Saurabh, Tripathi, Deeksha, Khubaib, Mohd, Kumar, Ashutosh, Sheikh, Javaid A., Sumanlatha, Gaddam, Ehtesham, Nasreen Z., Hasnain, Seyed E.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310130/
https://ncbi.nlm.nih.gov/pubmed/28261567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00038
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