Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype

BACKGROUND: Microglia and its polarization play critical roles in intracerebral hemorrhage-induced secondary brain injury. Programmed death protein 1/programmed death-ligand 1 has been reported to regulate neuroimmune cell functions. Signal transducers and activators of transcription 1 participate i...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Wu, Jie, Sun, Liang, Li, Haiying, Shen, Haitao, Zhai, Weiwei, Yu, Zhengquan, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310076/
https://ncbi.nlm.nih.gov/pubmed/28196545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0790-0
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