CD63 Regulates Epstein-Barr Virus LMP1 Exosomal Packaging, Enhancement of Vesicle Production, and Noncanonical NF-κB Signaling

Latent membrane protein 1 (LMP1) is an Epstein-Barr virus (EBV)-encoded oncoprotein that is packaged into small extracellular vesicles (EVs) called exosomes. Trafficking of LMP1 into multivesicular bodies (MVBs) alters the content and function of exosomes. LMP1-modified exosomes enhance the growth,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Hurwitz, Stephanie N., Nkosi, Dingani, Conlon, Meghan M., York, Sara B., Liu, Xia, Tremblay, Deanna C., Meckes, David G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Transformation and Oncogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309960/
https://ncbi.nlm.nih.gov/pubmed/27974566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02251-16
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