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Recombinant vacuolar iron transporter family homologue PfVIT from human malaria-causing Plasmodium falciparum is a Fe(2+)/H(+)exchanger

Vacuolar iron transporters (VITs) are a poorly understood family of integral membrane proteins that can function in iron homeostasis via sequestration of labile Fe(2+) into vacuolar compartments. Here we report on the heterologous overexpression and purification of PfVIT, a vacuolar iron transporter...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Labarbuta, Paola, Duckett, Katie, Botting, Catherine H., Chahrour, Osama, Malone, John, Dalton, John P., Law, Christopher J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309874/
https://ncbi.nlm.nih.gov/pubmed/28198449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42850
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