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SIRT1 plays a neuroprotective role in traumatic brain injury in rats via inhibiting the p38 MAPK pathway

Traumatic brain injury (TBI) is a major cause of disability and death in patients who experience a traumatic injury. Mitochondrial dysfunction is one of the main factors contributing to secondary injury in TBI-associated brain damage. Evidence of compromised mitochondrial function after TBI has been...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Yang, Hong, Gu, Zheng-tao, Li, Li, Maegele, Mac, Zhou, Bi-ying, Li, Feng, Zhao, Ming, Zhao, Ke-sen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309757/
https://ncbi.nlm.nih.gov/pubmed/28017962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.130
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