Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients

Objective. Trauma patients (TP) frequently develop an imbalanced immune response that often causes infectious postinjury complications. Monocytes show a diminished capability of both producing proinflammatory cytokines and antigen presentation after trauma. TLR2, TLR4, and TLR9 recognize pathogens a...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Heftrig, David, Sturm, Ramona, Oppermann, Elsie, Kontradowitz, Kerstin, Jurida, Katrin, Schimunek, Lukas, Woschek, Mathias, Marzi, Ingo, Relja, Borna
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309437/
https://ncbi.nlm.nih.gov/pubmed/28255201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2608349
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