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The Autophagy Level Is Increased in the Synovial Tissues of Patients with Active Rheumatoid Arthritis and Is Correlated with Disease Severity

Rheumatoid arthritis (RA) is a complex and not fully understood autoimmune disease associated with multijoint damage. The main effector cells, the synovial fibroblasts, are apoptosis resistant and hyperplastic which indicate that autophagy level is high in synovial tissue. Real-time PCR, immunocytoc...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Zhu, Li, Wang, Huaizhou, Wu, Yu, He, Zhengwen, Qin, Yanghua, Shen, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309404/
https://ncbi.nlm.nih.gov/pubmed/28255205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7623145
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