Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer’s disease

Glycogen synthase kinase-3β (GSK-3β) is a serine-threonine kinase implicated in multiple processes and signaling pathways. Its dysregulation is associated with different pathological conditions including Alzheimer’s disease (AD). Here we demonstrate how changes in GSK-3β activity and/or levels regul...

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Veröffentlicht in:Cell Mol Life Sci
Hauptverfasser: Fuster-Matanzo, Almudena, Jurado-Arjona, Jerónimo, Benvegnù, Stefano, García, Esther, Martín-Maestro, Patricia, Gómez-Sintes, Raquel, Hernández, Félix, Ávila, Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309299/
https://ncbi.nlm.nih.gov/pubmed/27832289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2408-6
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