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IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia

The mild neuroinflammation hypothesis of schizophrenia was introduced by Bechter in 2001. It has been hypothesized that a hypofunction of glutamatergic signaling via N-methyl-D-aspartate receptors (NMDARs) and hyperactivation of dopamine D2 receptors play a role in schizophrenia. The triplet puzzle...

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Pubblicato in:Front Psychiatry
Autori principali: Borroto-Escuela, Dasiel O., Tarakanov, Alexander O., Bechter, Karl, Fuxe, Kjell
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309215/
https://ncbi.nlm.nih.gov/pubmed/28261115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2017.00024
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