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Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7

In C. elegans, removal of the germline triggers molecular events in the neighboring intestine, which sends an anti-aging signal to the rest of the animal. In this study, we identified an innate immunity related gene, named irg-7, as a novel mediator of longevity in germlineless animals. We consider...

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Foilsithe in:PLoS Genet
Main Authors: Yunger, Elad, Safra, Modi, Levi-Ferber, Mor, Haviv-Chesner, Anat, Henis-Korenblit, Sivan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308781/
https://ncbi.nlm.nih.gov/pubmed/28196094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006577
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