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Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid–Independent Pathway

PURPOSE: Mutations in the CYP1B1 gene are the most commonly identified genetic causes of primary infantile-onset glaucoma. Despite this disease association, the role of CYP1B1 in eye development and its in vivo substrate remain unknown. In the present study, we used zebrafish to elucidate the mechan...

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Bibliografski detalji
Izdano u:Invest Ophthalmol Vis Sci
Glavni autori: Williams, Antionette L., Eason, Jessica, Chawla, Bahaar, Bohnsack, Brenda L.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308778/
https://ncbi.nlm.nih.gov/pubmed/28192799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20235
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