Increased Retinal Oxygen Metabolism Precedes Microvascular Alterations in Type 1 Diabetic Mice

PURPOSE: To investigate inner retinal oxygen metabolic rate (IRMRO(2)) during early stages of type 1 diabetes in a transgenic mouse model. METHODS: In current study, we involved seven diabetic mice (Akita/+, TSP1(−/−)) and seven control mice (TSP1(−/−)), and applied visible-light optical coherence t...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Liu, Wenzhong, Wang, Shoujian, Soetikno, Brian, Yi, Ji, Zhang, Kevin, Chen, Siyu, Linsenmeier, Robert A., Sorenson, Christine M., Sheibani, Nader, Zhang, Hao F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308771/
https://ncbi.nlm.nih.gov/pubmed/28535269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20600
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