Sirolimus and metformin synergistically inhibit hepatocellular carcinoma cell proliferation and improve long-term survival in patients with HCC related to hepatitis B virus induced cirrhosis after liver transplantation

Immunosuppressive agents used postoperatively after liver transplantation (LT) for hepatocellular carcinoma (HCC) favor recurrence and metastasis. Therefore, new effective immunosuppressants are needed. This retrospective study assessed combined sirolimus and metformin on survival of HCC patients af...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shen, Chuan, Peng, Chenghong, Shen, Baiyong, Zhu, Zhecheng, Xu, Ning, Li, Tao, Xie, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308754/
https://ncbi.nlm.nih.gov/pubmed/27577068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11591
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