Sirolimus and metformin synergistically inhibit hepatocellular carcinoma cell proliferation and improve long-term survival in patients with HCC related to hepatitis B virus induced cirrhosis after liver transplantation

Immunosuppressive agents used postoperatively after liver transplantation (LT) for hepatocellular carcinoma (HCC) favor recurrence and metastasis. Therefore, new effective immunosuppressants are needed. This retrospective study assessed combined sirolimus and metformin on survival of HCC patients af...

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Publicado en:Oncotarget
Autores principales: Shen, Chuan, Peng, Chenghong, Shen, Baiyong, Zhu, Zhecheng, Xu, Ning, Li, Tao, Xie, Junjie
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308754/
https://ncbi.nlm.nih.gov/pubmed/27577068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11591
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