Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature

Pancreatic ductal adenocarcinoma (PDAC) is the most challenging type of cancer to treat, with a 5-year survival rate of <10%. Furthermore, because of the large portion of the inoperable cases, it is difficult to obtain specimens to study the biology of the tumors. Therefore, a patient-derived xen...

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Publicado en:Oncotarget
Autores principales: Jung, Jaeyun, Lee, Cue Hyunkyu, Seol, Hyang Sook, Choi, Yeon Sook, Kim, Eunji, Lee, Eun Ji, Rhee, Je-Keun, Singh, Shree Ram, Jun, Eun Sung, Han, Buhm, Hong, Seung Mo, Kim, Song Cheol, Chang, Suhwan
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308744/
https://ncbi.nlm.nih.gov/pubmed/27613834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11530
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