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Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1

Hypoxia activates hypoxia-inducible factor 1, which promotes the progression of malignancy by stimulating angiogenesis and by augmenting the ability of tumors to survive. Thus, HIF-1 is one of the most compelling targets for treating cancers. The aim of this study was to find a small molecule that i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Choi, Yong-Joon, Shin, Hyun-Woo, Chun, Yang-Sook, Leutou, Alain Simplice, Son, Byeng Wha, Park, Jong-Wan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308714/
https://ncbi.nlm.nih.gov/pubmed/27613833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11529
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