Ataxia-telangiectasia mutated activation mediates tumor necrosis factor-alpha induced MMP-13 up-regulation and metastasis in lung cancer cells

Despite that ataxia-telangiectasia mutated (ATM) is involved in IL-6 promoted lung cancer chemotherapeutic resistance and metastasis, the exact role of ATM in tumor necrosis factor-alpha (TNF-α) increasing tumor migration is still elusive. In the present study, we demonstrated that TNF-α promoted lu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yan, Hong Qiong, Zhang, Di, Shi, Yuan Yuan, You, Xiang, Shi, Lei, Li, Qing, Gao, Feng Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308711/
https://ncbi.nlm.nih.gov/pubmed/27556690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11386
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