Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

Epithelial to mesenchymal transition (EMT) is a developmental program that has been implicated in progression, metastasis and therapeutic resistance of some carcinomas. To identify genes whose overexpression drives EMT, we screened a lentiviral expression library of 17000 human open reading frames (...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Škalamera, Dubravka, Dahmer-Heath, Mareike, Stevenson, Alexander J., Pinto, Cletus, Shah, Esha T., Daignault, Sheena M., Said, Nur Akmarina B.M., Davis, Melissa, Haass, Nikolas K., Williams, Elizabeth D., Hollier, Brett G., Thompson, Erik W., Gabrielli, Brian, Gonda, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308632/
https://ncbi.nlm.nih.gov/pubmed/27876705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11314
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