Genetic Ablation of Phosphatidylcholine Transfer Protein/StarD2 in ob/ob Mice Improves Glucose Tolerance Without Increasing Energy Expenditure

OBJECTIVE: Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is highly expressed in liver and oxidative tissues. PC-TP promotes hepatic glucose production during fasting and aggravates glucose intolerance in high fat fed mice. However, because PC-TP also suppresses thermogenesis in brown...

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Bibliografske podrobnosti
izdano v:Metabolism
Main Authors: Krisko, Tibor I., LeClair, Katherine B., Cohen, David E.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308448/
https://ncbi.nlm.nih.gov/pubmed/28183446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2016.11.012
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