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RnlB Antitoxin of the Escherichia coli RnlA-RnlB Toxin–Antitoxin Module Requires RNase HI for Inhibition of RnlA Toxin Activity

The Escherichia coli RnlA-RnlB toxin–antitoxin system is related to the anti-phage mechanism. Under normal growth conditions, an RnlA toxin with endoribonuclease activity is inhibited by binding of its cognate RnlB antitoxin. After bacteriophage T4 infection, RnlA is activated by the disappearance o...

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Publicat a:Toxins (Basel)
Autors principals: Naka, Kenta, Qi, Dan, Yonesaki, Tetsuro, Otsuka, Yuichi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308261/
https://ncbi.nlm.nih.gov/pubmed/28085056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9010029
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