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Intraluminal Tranexamic Acid Inhibits Intestinal Sheddases and Mitigates Gut and Lung Injury and Inflammation in a Rodent Model of Hemorrhagic Shock
BACKGROUND: Intravenous tranexamic acid (TXA) is an effective adjunct after hemorrhagic shock (HS) due to its antifibrinolytic properties. TXA is also a serine protease inhibitor and recent laboratory data demonstrated that intraluminal TXA into the small bowel inhibited digestive proteases and prot...
Gorde:
| Argitaratua izan da: | J Trauma Acute Care Surg |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5308205/ https://ncbi.nlm.nih.gov/pubmed/27027557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001056 |
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