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Purified omega-conotoxin GVIA receptor of rat brain resembles a dihydropyridine-sensitive L-type calcium channel.

The omega-conotoxin GVIA (CTX) receptor has been purified 1900-fold to apparent homogeneity by monitoring both reversible binding of 125I-labeled CTX (125I-CTX) and photoincorporation of N-hydroxysuccinimidyl-4-azidobenzoate-125I-CTX (HSA-125I-CTX). Photoincorporation of HSA-125I-CTX into a 230-kDa...

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Published in:Proc Natl Acad Sci U S A
Main Authors: McEnery, M W, Snowman, A M, Sharp, A H, Adams, M E, Snyder, S H
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1991
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662383/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11095
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