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Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy
BACKGROUND: Bacterial toxins have evolved to an effective therapeutic option for cancer therapy. The Clostridium perfringens enterotoxin (CPE) is a pore-forming toxin with selective cytotoxicity. The transmembrane tight junction proteins claudin-3 and -4 are known high affinity CPE receptors. Their...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5307849/ https://ncbi.nlm.nih.gov/pubmed/28193196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3123-x |
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