Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer

BACKGROUND: Proliferation may predict response to neoadjuvant therapy of breast cancer and is commonly assessed by manual scoring of slides stained by immunohistochemistry (IHC) for Ki-67 similar to ER and PgR. This method carries significant intra- and inter-observer variability. Automatic scoring...

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Publicado en:BMC Cancer
Main Authors: Sinn, Hans-Peter, Schneeweiss, Andreas, Keller, Marius, Schlombs, Kornelia, Laible, Mark, Seitz, Julia, Lakis, Sotirios, Veltrup, Elke, Altevogt, Peter, Eidt, Sebastian, Wirtz, Ralph M., Marmé, Frederik
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307758/
https://ncbi.nlm.nih.gov/pubmed/28193205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3111-1
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