Pemafibrate, a novel selective peroxisome proliferator-activated receptor alpha modulator, improves the pathogenesis in a rodent model of nonalcoholic steatohepatitis

The efficacy of peroxisome proliferator-activated receptor α-agonists (e.g., fibrates) against nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) in humans is not known. Pemafibrate is a novel selective peroxisome proliferator-activated receptor α modulator that can maximiz...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Honda, Yasushi, Kessoku, Takaomi, Ogawa, Yuji, Tomeno, Wataru, Imajo, Kento, Fujita, Koji, Yoneda, Masato, Takizawa, Toshiaki, Saito, Satoru, Nagashima, Yoji, Nakajima, Atsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307366/
https://ncbi.nlm.nih.gov/pubmed/28195199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42477
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