Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury

The development of ventilator-induced lung injury (VILI) is still a major problem in mechanically ventilated patients. Low dose inhalation of hydrogen sulfide (H(2)S) during mechanical ventilation has been proven to prevent lung damage by limiting inflammatory responses in rodent models. However, th...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Spassov, Sashko Georgiev, Donus, Rosa, Ihle, Paul Mikael, Engelstaedter, Helen, Hoetzel, Alexander, Faller, Simone
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307128/
https://ncbi.nlm.nih.gov/pubmed/28250891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3715037
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