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Interleukin 2- and interleukin 5-induced changes in the binding of regulatory factors to the J-chain gene promoter.

In a primary immune response, B cells require signals from the T-cell lymphokines interleukins 2 and 5 (IL-2 and IL-5) to develop into IgM-secreting cells. One role of IL-2 and IL-5 is to activate transcription of the gene encoding the IgM joining component, the J chain. In this study the activation...

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Библиографические подробности
Главные авторы: McFadden, H J, Koshland, M E
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC53066/
https://ncbi.nlm.nih.gov/pubmed/1763018
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