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Intranasal Administration of the Antisecretory Peptide AF-16 Reduces Edema and Improves Cognitive Function Following Diffuse Traumatic Brain Injury in the Rat

A synthetic peptide with antisecretory activity, antisecretory factor (AF)-16, improves injury-related deficits in water and ion transport and decreases intracranial pressure after experimental cold lesion injury and encephalitis although its role in traumatic brain injury (TBI) is unknown. AF-16 or...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Clausen, Fredrik, Hansson, Hans-Arne, Raud, Johan, Marklund, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306199/
https://ncbi.nlm.nih.gov/pubmed/28261150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00039
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