Ascorbic acid protects against endogenous oxidative DNA damage in human sperm.

Damage to the DNA of germ cells can lead to mutation, which may result in birth defects, genetic diseases, and cancer. The very high endogenous rate of oxidative DNA damage and the importance of dietary ascorbic acid (AA) in preventing this damage has prompted an examination of these factors in huma...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fraga, C G, Motchnik, P A, Shigenaga, M K, Helbock, H J, Jacob, R A, Ames, B N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1763015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11003
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