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Clonidine Reduces Norepinephrine and Improves Bone Marrow Function in a Rodent Model of Lung Contusion, Hemorrhagic Shock and Chronic Stress

BACKGROUND: Propranolol has been shown previously to restore bone marrow function and improve anemia after lung contusion/hemorrhagic shock. We hypothesized that daily clonidine administration would inhibit central sympathetic outflow and restore bone marrow function in our rodent model of lung cont...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Surgery
Hauptverfasser: Alamo, Ines G., Kannan, Kolenkode B., Ramos, Harry, Loftus, Tyler J., Efron, Philip A., Mohr, Alicia M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305616/
https://ncbi.nlm.nih.gov/pubmed/27742030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2016.08.043
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