Bead-based immunoassay allows sub-picogram detection of histidine-rich protein 2 from Plasmodium falciparum and estimates reliability of malaria rapid diagnostic tests

Detection of histidine-rich protein 2 (HRP2) from the malaria parasite Plasmodium falciparum provides evidence for active or recent infection, and is utilized for both diagnostic and surveillance purposes, but current laboratory immunoassays for HRP2 are hindered by low sensitivities and high costs....

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Udgivet i:PLoS One
Main Authors: Rogier, Eric, Plucinski, Mateusz, Lucchi, Naomi, Mace, Kimberly, Chang, Michelle, Lemoine, Jean Frantz, Candrinho, Baltazar, Colborn, James, Dimbu, Rafael, Fortes, Filomeno, Udhayakumar, Venkatachalam, Barnwell, John
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305216/
https://ncbi.nlm.nih.gov/pubmed/28192523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172139
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