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Drug versus placebo randomized controlled trials in neonates: A review of ClinicalTrials.gov registry

BACKGROUND: Despite specific initiatives and identified needs, most neonatal drugs are still used off-label, with variable dosage administrations and schedules. In high risk preterm and term neonates, drug evaluation is challenging and randomized controlled trials (RCT) are difficult to conduct and...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Desselas, Emilie, Pansieri, Claudia, Leroux, Stephanie, Bonati, Maurizio, Jacqz-Aigrain, Evelyne
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305102/
https://ncbi.nlm.nih.gov/pubmed/28192509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171760
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