Insights into Pyrazinamidase and DNA Gyrase Protein Structures in Resistant and Susceptible Clinical Isolates of Mycobacterium tuberculosis

BACKGROUND: Mutations in pncA and gyrA genes cause pyrazinamide (PZA) and fluroquinolone resistance in Mycobacterium tuberculosis (MTB). In the present study, structures of pyrazinamidase (PZase) and DNA gyrase proteins were studied in resistant and susceptible clinical isolates of MTB. MATERIALS AN...

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Publicado no:Tanaffos
Main Authors: Ahmadi, Azam, Nazari, Raziyeh, Arjomandzadegan, Mohammad, Zolfaghari, Mohammad Reza, Vahidi, Vahideh, Poolad, Toktam, Kahbazi, Manijeh, Sadrnia, Maryam, Tousheh, Mojtaba, Rafiee, Pourya
Formato: Artigo
Idioma:Inglês
Publicado em: National Research Institute of Tuberculosis and Lung Disease 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304958/
https://ncbi.nlm.nih.gov/pubmed/28210279
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