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Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release

Adjuvants enhance immunogenicity of vaccines through either targeted antigen delivery or stimulation of immune receptors. Three cationic nanoparticle formulations were evaluated for their potential as carriers for a DNA vaccine, and muramyl dipeptide (MDP) as immunostimulatory agent, to induce and i...

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Bibliografiske detaljer
Udgivet i:Nanomaterials (Basel)
Main Authors: Poecheim, Johanna, Heuking, Simon, Brunner, Livia, Barnier-Quer, Christophe, Collin, Nicolas, Borchard, Gerrit
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304807/
https://ncbi.nlm.nih.gov/pubmed/28347123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano5042317
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