Utilization of Enzyme-Immobilized Mesoporous Silica Nanocontainers (IBN-4) in Prodrug-Activated Cancer Theranostics

To develop a carrier for use in enzyme prodrug therapy, Horseradish peroxidase (HRP) was immobilized onto mesoporous silica nanoparticles (IBN-4: Institute of Bioengineering and Nanotechnology), where the nanoparticle surfaces were functionalized with 3-aminopropyltrimethoxysilane and further conjug...

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Publicat a:Nanomaterials (Basel)
Autors principals: Hung, Bau-Yen, Kuthati, Yaswanth, Kankala, Ranjith Kumar, Kankala, Shravankumar, Deng, Jin-Pei, Liu, Chen-Lun, Lee, Chia-Hung
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304787/
https://ncbi.nlm.nih.gov/pubmed/28347114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano5042169
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