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Therapeutics Based on Stop Codon Readthrough
Nonsense suppression therapy encompasses approaches aimed at suppressing translation termination at in-frame premature termination codons (PTCs, also known as nonsense mutations) to restore deficient protein function. In this review, we examine the current status of PTC suppression as a therapy for...
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| Publicado no: | Annu Rev Genomics Hum Genet |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5304456/ https://ncbi.nlm.nih.gov/pubmed/24773318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genom-091212-153527 |
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