Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.

Rheumatoid arthritis (RA) is a disease affecting the synovial membranes of articulating joints that is thought to result from T-cell-mediated autoimmune phenomena. T cells responsible for the pathogenesis of RA are likely present in that fraction of synovial T cells that expresses the interleukin 2...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Howell, M D, Diveley, J P, Lundeen, K A, Esty, A, Winters, S T, Carlo, D J, Brostoff, S W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53044/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1660155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10921
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