Accelerated biodegradation of silk sutures through matrix metalloproteinase activation by incorporating 4-hexylresorcinol

Silk suture material is primarily composed of silk fibroin and regarded as a non-resorbable material. It is slowly degraded by proteolysis when it is implanted into the body. 4-Hexylresorcinol (4HR) is a well-known antiseptic. In this study, the biodegradability of 4HR-incorporated silk sutures were...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Jo, You-Young, Kweon, HaeYong, Kim, Dae-Won, Kim, Min-Keun, Kim, Seong-Gon, Kim, Jwa-Young, Chae, Weon-Sik, Hong, Sam-Pyo, Park, Young-Hwan, Lee, Si Young, Choi, Je-Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304327/
https://ncbi.nlm.nih.gov/pubmed/28205580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42441
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