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Ca(2+) Selective Host Rotaxane Is Highly Toxic Against Prostate Cancer Cells

[Image: see text] New therapies are needed to eradicate androgen resistant, prostate cancer. Prostate cancer usually metastasizes to bone where the concentration of calcium is high, making Ca(2+) a promising toxin. Ionophores can deliver metal cations into cells, but are currently too toxic for huma...

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Bibliografiska uppgifter
I publikationen:ACS Med Chem Lett
Huvudupphovsmän: Smithrud, David B., Powers, Lucas, Lunn, Jennifer, Abernathy, Scott, Peschka, Michael, Ho, Shuk-mei, Tarapore, Pheruza
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2017
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304289/
https://ncbi.nlm.nih.gov/pubmed/28197305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00347
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