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Ca(2+) Selective Host Rotaxane Is Highly Toxic Against Prostate Cancer Cells
[Image: see text] New therapies are needed to eradicate androgen resistant, prostate cancer. Prostate cancer usually metastasizes to bone where the concentration of calcium is high, making Ca(2+) a promising toxin. Ionophores can deliver metal cations into cells, but are currently too toxic for huma...
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| Veröffentlicht in: | ACS Med Chem Lett |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2017
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5304289/ https://ncbi.nlm.nih.gov/pubmed/28197305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00347 |
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