Concentration-dependent oligomerization of an alpha-helical antifreeze polypeptide makes it hyperactive

A supersoluble 40-residue type I antifreeze protein (AFP) was discovered in a righteye flounder, the barfin plaice (bp). Unlike all other AFPs characterized to date, bpAFP transitions from moderately-active to hyperactive with increasing concentration. At sub-mM concentrations, bpAFP bound to pyrami...

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Vydáno v:Sci Rep
Hlavní autoři: Mahatabuddin, Sheikh, Hanada, Yuichi, Nishimiya, Yoshiyuki, Miura, Ai, Kondo, Hidemasa, Davies, Peter L., Tsuda, Sakae
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304152/
https://ncbi.nlm.nih.gov/pubmed/28211917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42501
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