Icariin Inhibits AMPK-Dependent Autophagy and Adipogenesis in Adipocytes In vitro and in a Model of Graves' Orbitopathy In vivo

Graves' orbitopathy (GO), an extrathyroidal manifestation of Graves' disease, is an inflammatory autoimmune disorder of the orbit that involves the differentiation of precursor cells into mature adipocytes and retro-orbital adipose tissue accumulation. Here, we examined the involvement of...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Li, Hong, Yuan, Yifei, Zhang, Yali, Zhang, Xia, Gao, Long, Xu, Rongjuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303717/
https://ncbi.nlm.nih.gov/pubmed/28243204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00045
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