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Conditional deletion of pejvakin in adult outer hair cells causes progressive hearing loss in mice

Mutations in the Pejvakin (Pjvk) gene cause autosomal recessive hearing loss DFNB59 with audiological features of auditory neuropathy spectrum disorder (ANSD) or cochlear dysfunction. The precise mechanisms underlying the variable clinical phenotypes of DFNB59 remain unclear. Here, we demonstrate th...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Harris, Suzan L., Kazmierczak, Marcin, Pangrši, Tina, Shah, Prahar, Chuchvara, Nadiya, Barrantes-Freer, Alonso, Moser, Tobias, Schwander, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303641/
https://ncbi.nlm.nih.gov/pubmed/28089576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.12.055
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